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Nonaplex PCR using Cliffhanger primers to identify diarrhoeagenic Escherichia coli from crude lysates of human faecal samples

Sensitive, probe-based detection of multiple DNA targets is limited by the competitive reannealing of the antiparallel duplex DNA helix with the complementary DNA strand. To address this, we developed Cliffhanger primers, which create single-stranded DNA overhangs on PCR amplicons while simultaneous...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Schneider, Uffe Vest, Mikkelsen, Nikolaj Dam, Scheutz, Flemming, Friis-Møller, Alice, Lisby, Gorm
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019694/
https://ncbi.nlm.nih.gov/pubmed/29944710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199766
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