Pharmacokinetics, pharmacodynamics, and tolerability of verinurad, a selective uric acid reabsorption inhibitor, in healthy Japanese and non-Asian male subjects

PURPOSE: Verinurad (RDEA3170) is a selective uric acid reabsorption inhibitor in clinical development for treatment of gout and asymptomatic hyperuricemia. This study evaluated verinurad pharmacokinetics, pharmacodynamics, and tolerability in healthy Japanese and non-Asian adult male subjects. METHO...

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Bibliographic Details
Published in:Drug Des Devel Ther
Main Authors: Hall, Jesse, Gillen, Michael, Liu, Sha, Miner, Jeffrey N, Valdez, Shakti, Shen, Zancong, Lee, Caroline
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2018
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018888/
https://ncbi.nlm.nih.gov/pubmed/29950814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S152659
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