lincROR influences the stemness and crizotinib resistance in EML–ALK(+) non-small-cell lung cancer cells

INTRODUCTION: Echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4–ALK) is identified as an important pathogenic factor in patients with non-small-cell lung cancer (NSCLC) and could induce a stem-like phenotype in NSCLC cells. Crizotinib is commonly used for EML4–ALK(+)...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Yang, Yonghua, Huang, Jingyu, Xie, Nianlin, Huang, Hu, Xu, Shaogan, Cai, Jun, Qi, Shuai
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018841/
https://ncbi.nlm.nih.gov/pubmed/29950868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S165290
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