ALK inhibitor PF02341066 (crizotinib) increases sensitivity to radiation in non-small cell lung cancer expressing EML4-ALK

Crizotinib (PF02341066) is a tyrosine kinase inhibitor of ALK that has been shown to selectively inhibit growth of cancer cells that harbor the EML4-ALK fusion, found in a subset of patients with non-small cell lung cancer (NSCLC). While in clinical trials PF02341066 has shown a significant therapeu...

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Главные авторы: Sun, Yunguang, Nowak, Kamila A., Zaorsky, Nicholas G., Winchester, Chia-Lin, Dalal, Kunal, Giacalone, Nicholas J., Liu, Ningbo, Werner-Wasik, Maria, Wasik, Mariusz A., Dicker, Adam P., Lu, Bo
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3651772/
https://ncbi.nlm.nih.gov/pubmed/23443800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-12-0868
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