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S-nitrosation of protein phosphatase 1 mediates alcohol-induced ciliary dysfunction
Alcohol use disorder (AUD) is a strong risk factor for development and mortality of pneumonia. Mucociliary clearance, a key innate defense against pneumonia, is perturbed by alcohol use. Specifically, ciliated airway cells lose the ability to increase ciliary beat frequency (CBF) to β-agonist stimul...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6018795/ https://ncbi.nlm.nih.gov/pubmed/29946131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27924-x |
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