Alcohol drives S-nitrosylation and redox activation of protein phosphatase 1, causing bovine airway cilia dysfunction

Individuals with alcohol (ethanol)-use disorders are at increased risk for lung infections, in part, due to defective mucociliary clearance driven by motile cilia in the airways. We recently reported that isolated, demembranated bovine cilia (axonemes) are capable of producing nitric oxide ((∙)NO) w...

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Bibliographic Details
Published in:Am J Physiol Lung Cell Mol Physiol
Main Authors: Price, Michael E., Pavlik, Jacqueline A., Liu, Miao, Ding, Shi-Jian, Wyatt, Todd A., Sisson, Joseph H.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2017
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Rapid Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374300/
https://ncbi.nlm.nih.gov/pubmed/28062487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00513.2016
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