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Alcohol drives S-nitrosylation and redox activation of protein phosphatase 1, causing bovine airway cilia dysfunction

Individuals with alcohol (ethanol)-use disorders are at increased risk for lung infections, in part, due to defective mucociliary clearance driven by motile cilia in the airways. We recently reported that isolated, demembranated bovine cilia (axonemes) are capable of producing nitric oxide ((∙)NO) w...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Price, Michael E., Pavlik, Jacqueline A., Liu, Miao, Ding, Shi-Jian, Wyatt, Todd A., Sisson, Joseph H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374300/
https://ncbi.nlm.nih.gov/pubmed/28062487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00513.2016
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