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Alcohol drives S-nitrosylation and redox activation of protein phosphatase 1, causing bovine airway cilia dysfunction

Individuals with alcohol (ethanol)-use disorders are at increased risk for lung infections, in part, due to defective mucociliary clearance driven by motile cilia in the airways. We recently reported that isolated, demembranated bovine cilia (axonemes) are capable of producing nitric oxide ((∙)NO) w...

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Bibliografiska uppgifter
I publikationen:Am J Physiol Lung Cell Mol Physiol
Huvudupphovsmän: Price, Michael E., Pavlik, Jacqueline A., Liu, Miao, Ding, Shi-Jian, Wyatt, Todd A., Sisson, Joseph H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374300/
https://ncbi.nlm.nih.gov/pubmed/28062487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00513.2016
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