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Alcohol drives S-nitrosylation and redox activation of protein phosphatase 1, causing bovine airway cilia dysfunction

Individuals with alcohol (ethanol)-use disorders are at increased risk for lung infections, in part, due to defective mucociliary clearance driven by motile cilia in the airways. We recently reported that isolated, demembranated bovine cilia (axonemes) are capable of producing nitric oxide ((∙)NO) w...

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Detalles Bibliográficos
Publicado en:Am J Physiol Lung Cell Mol Physiol
Main Authors: Price, Michael E., Pavlik, Jacqueline A., Liu, Miao, Ding, Shi-Jian, Wyatt, Todd A., Sisson, Joseph H.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374300/
https://ncbi.nlm.nih.gov/pubmed/28062487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00513.2016
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