l-Phenylalanine Restores Vascular Function in Spontaneously Hypertensive Rats Through Activation of the GCH1-GFRP Complex

Reduced nitric oxide (NO) bioavailability correlates with impaired cardiovascular function. NO is extremely labile and has been challenging to develop as a therapeutic agent. However, NO bioavailability could be enhanced by pharmacologically targeting endogenous NO regulatory pathways. Tetrahydrobio...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Heikal, Lamia, Starr, Anna, Hussein, Dania, Prieto-Lloret, Jesus, Aaronson, Phil, Dailey, Lea Ann, Nandi, Manasi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
PRECLINICAL RESEARCH
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018612/
https://ncbi.nlm.nih.gov/pubmed/29963647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.01.015
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