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The multifaceted allosteric regulation of Aurora kinase A

The protein kinase Aurora A (AurA) is essential for the formation of bipolar mitotic spindles in all eukaryotic organisms. During spindle assembly, AurA is activated through two different pathways operating at centrosomes and on spindle microtubules. Recent studies have revealed that these pathways...

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Bibliographic Details
Published in:Biochem J
Main Author: Levinson, Nicholas Mark
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018539/
https://ncbi.nlm.nih.gov/pubmed/29946042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20170771
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