Evolutionary Adaptation and Amyloid Formation: Does the Reduced Amyloidogenicity and Cytotoxicity of Ursine Amylin Contribute to the Metabolic Adaption of Bears and Polar Bears?

Much of our knowledge of diabetes is derived from studies of rodent models. An alternative approach explores evolutionary solutions to physiological stress by studying organisms that face challenging metabolic environments. Polar bears eat an enormously lipid-rich diet without deleterious metabolic...

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Detalhes bibliográficos
Publicado no:Isr J Chem
Main Authors: Akter, Rehana, Abedini, Andisheh, Ridgway, Zachary, Zhang, Xiaoxue, Kleinberg, Joel, Schmidt, Ann Marie, Raleigh, Daniel P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018008/
https://ncbi.nlm.nih.gov/pubmed/29955200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijch.201600081
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