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Synthesis and Evaluation of the Tumor Cell Growth Inhibitory Potential of New Putative HSP90 Inhibitors

Background: Heat shock protein 90 (HSP90) is a well-known target for cancer therapy. In a previous work, some of us have reported a series of 3-aryl-naphtho[2,3-d]isoxazole-4,9-diones as inhibitors of HSP90. Methods: In the present work, various compounds with new chromenopyridinone and thiochromeno...

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Detalles Bibliográficos
Publicado en:Molecules
Main Authors: Bizarro, Ana, Sousa, Diana, Lima, Raquel T., Musso, Loana, Cincinelli, Raffaella, Zuco, Vantina, De Cesare, Michelandrea, Dallavalle, Sabrina, Vasconcelos, M. Helena
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017909/
https://ncbi.nlm.nih.gov/pubmed/29438315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23020407
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