The Fungal Metabolite Eurochevalierine, a Sequiterpene Alkaloid, Displays Anti-Cancer Properties through Selective Sirtuin 1/2 Inhibition

NAD(+)-dependent histone deacetylases (sirtuins) are implicated in cellular processes such as proliferation, DNA repair, and apoptosis by regulating gene expression and the functions of numerous proteins. Due to their key role in cells, the discovery of small molecule sirtuin modulators has been of...

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發表在:Molecules
Main Authors: Schnekenburger, Michael, Mathieu, Véronique, Lefranc, Florence, Jang, Jun Young, Masi, Marco, Kijjoa, Anake, Evidente, Antonio, Kim, Hyun-Jung, Kiss, Robert, Dicato, Mario, Han, Byung Woo, Diederich, Marc
格式: Artigo
語言:Inglês
出版: MDPI 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017873/
https://ncbi.nlm.nih.gov/pubmed/29401749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23020333
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