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The Fungal Metabolite Eurochevalierine, a Sequiterpene Alkaloid, Displays Anti-Cancer Properties through Selective Sirtuin 1/2 Inhibition

NAD(+)-dependent histone deacetylases (sirtuins) are implicated in cellular processes such as proliferation, DNA repair, and apoptosis by regulating gene expression and the functions of numerous proteins. Due to their key role in cells, the discovery of small molecule sirtuin modulators has been of...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Schnekenburger, Michael, Mathieu, Véronique, Lefranc, Florence, Jang, Jun Young, Masi, Marco, Kijjoa, Anake, Evidente, Antonio, Kim, Hyun-Jung, Kiss, Robert, Dicato, Mario, Han, Byung Woo, Diederich, Marc
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017873/
https://ncbi.nlm.nih.gov/pubmed/29401749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23020333
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