The Fungal Metabolite Eurochevalierine, a Sequiterpene Alkaloid, Displays Anti-Cancer Properties through Selective Sirtuin 1/2 Inhibition

NAD(+)-dependent histone deacetylases (sirtuins) are implicated in cellular processes such as proliferation, DNA repair, and apoptosis by regulating gene expression and the functions of numerous proteins. Due to their key role in cells, the discovery of small molecule sirtuin modulators has been of...

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Dettagli Bibliografici
Pubblicato in:Molecules
Autori principali: Schnekenburger, Michael, Mathieu, Véronique, Lefranc, Florence, Jang, Jun Young, Masi, Marco, Kijjoa, Anake, Evidente, Antonio, Kim, Hyun-Jung, Kiss, Robert, Dicato, Mario, Han, Byung Woo, Diederich, Marc
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017873/
https://ncbi.nlm.nih.gov/pubmed/29401749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23020333
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