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Synaptic Alterations in Mouse Models for Alzheimer Disease—A Special Focus on N-Truncated Abeta 4-42

This commentary reviews the role of the Alzheimer amyloid peptide Aβ on basal synaptic transmission, synaptic short-term plasticity, as well as short- and long-term potentiation in transgenic mice, with a special focus on N-terminal truncated Aβ(4-42). Aβ(4-42) is highly abundant in the brain of Alz...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Dietrich, Katharina, Bouter, Yvonne, Müller, Michael, Bayer, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017701/
https://ncbi.nlm.nih.gov/pubmed/29561816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23040718
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