In Silico and in Vitro-Guided Identification of Inhibitors of Alkylquinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa

Pseudomonas aeruginosa is a major opportunistic pathogen in cystic fibrosis, wound and nosocomial infections, posing a serious burden to public health, due to its antibiotic resistance. The P. aeruginosa Pseudomonas Quinolone System (pqs) quorum sensing system, driven by the activation of the transc...

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Publicat a:Molecules
Autors principals: Soukarieh, Fadi, Vico Oton, Eduard, Dubern, Jean-Frédéric, Gomes, Janice, Halliday, Nigel, de Pilar Crespo, Maria, Ramírez-Prada, Jonathan, Insuasty, Braulio, Abonia, Rodrigo, Quiroga, Jairo, Heeb, Stephan, Williams, Paul, Stocks, Michael J., Cámara, Miguel
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017655/
https://ncbi.nlm.nih.gov/pubmed/29382099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23020257
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