Bridging from Brain to Tumor Imaging: (S)-(−)- and (R)-(+)-[(18)F]Fluspidine for Investigation of Sigma-1 Receptors in Tumor-Bearing Mice †

Sigma-1 receptors (Sig1R) are highly expressed in various human cancer cells and hence imaging of this target with positron emission tomography (PET) can contribute to a better understanding of tumor pathophysiology and support the development of antineoplastic drugs. Two Sig1R-specific radiolabeled...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Kranz, Mathias, Bergmann, Ralf, Kniess, Torsten, Belter, Birgit, Neuber, Christin, Cai, Zhengxin, Deng, Gang, Fischer, Steffen, Zhou, Jiangbing, Huang, Yiyun, Brust, Peter, Deuther-Conrad, Winnie, Pietzsch, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017399/
https://ncbi.nlm.nih.gov/pubmed/29558382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23030702
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