Enrichment of B cell receptor signaling and epidermal growth factor receptor pathways in monoclonal gammopathy of undetermined significance: a genome-wide genetic interaction study

BACKGROUND: Recent identification of 10 germline variants predisposing to monoclonal gammopathy of undetermined significance (MGUS) explicates genetic dependency of this asymptomatic precursor condition with multiple myeloma (MM). Yet much of genetic burden as well as functional links remain unexpla...

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Publicat a:Mol Med
Autors principals: Chattopadhyay, Subhayan, Thomsen, Hauke, da Silva Filho, Miguel Inacio, Weinhold, Niels, Hoffmann, Per, Nöthen, Markus M., Marina, Arendt, Jöckel, Karl-Heinz, Schmidt, Börge, Pechlivanis, Sonali, Langer, Christian, Goldschmidt, Hartmut, Hemminki, Kari, Försti, Asta
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016882/
https://ncbi.nlm.nih.gov/pubmed/30134812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0031-8
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