Enrichment of B cell receptor signaling and epidermal growth factor receptor pathways in monoclonal gammopathy of undetermined significance: a genome-wide genetic interaction study

BACKGROUND: Recent identification of 10 germline variants predisposing to monoclonal gammopathy of undetermined significance (MGUS) explicates genetic dependency of this asymptomatic precursor condition with multiple myeloma (MM). Yet much of genetic burden as well as functional links remain unexpla...

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Publicado en:Mol Med
Autores principales: Chattopadhyay, Subhayan, Thomsen, Hauke, da Silva Filho, Miguel Inacio, Weinhold, Niels, Hoffmann, Per, Nöthen, Markus M., Marina, Arendt, Jöckel, Karl-Heinz, Schmidt, Börge, Pechlivanis, Sonali, Langer, Christian, Goldschmidt, Hartmut, Hemminki, Kari, Försti, Asta
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016882/
https://ncbi.nlm.nih.gov/pubmed/30134812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0031-8
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