Enrichment of B cell receptor signaling and epidermal growth factor receptor pathways in monoclonal gammopathy of undetermined significance: a genome-wide genetic interaction study

BACKGROUND: Recent identification of 10 germline variants predisposing to monoclonal gammopathy of undetermined significance (MGUS) explicates genetic dependency of this asymptomatic precursor condition with multiple myeloma (MM). Yet much of genetic burden as well as functional links remain unexpla...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Chattopadhyay, Subhayan, Thomsen, Hauke, da Silva Filho, Miguel Inacio, Weinhold, Niels, Hoffmann, Per, Nöthen, Markus M., Marina, Arendt, Jöckel, Karl-Heinz, Schmidt, Börge, Pechlivanis, Sonali, Langer, Christian, Goldschmidt, Hartmut, Hemminki, Kari, Försti, Asta
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016882/
https://ncbi.nlm.nih.gov/pubmed/30134812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0031-8
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