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IL-6 is associated to IGF-1Ec upregulation and Ec peptide secretion, from prostate tumors

BACKGROUND: Ec peptide (PEc), resulting from the proteolytic cleavage of the IGF-1Ec isoform, is involved in prostate cancer progression and metastasis, whereas in muscle tissue, it is associated with the mobilization of satellite cells prior to repair. Our aim is to determine the physiological cond...

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Bibliografiske detaljer
Udgivet i:Mol Med
Main Authors: Armakolas, A., Dimakakos, A., Loukogiannaki, C., Armakolas, N., Antonopoulos, A., Florou, C., Tsioli, P., Papageorgiou, E., Alexandrou, T. P., Stathaki, M., Spinos, D., Pektasides, D., Patsouris, E., Koutsilieris, M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016866/
https://ncbi.nlm.nih.gov/pubmed/30134795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0003-z
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