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Oncogenic Role of the Ec Peptide of the IGF-1Ec Isoform in Prostate Cancer

IGF-1 is one of the key molecules in cancer biology; however, little is known about the role of the preferential expression of the premature IGF-1 isoforms in prostate cancer. We have examined the role of the cleaved COO– terminal peptide (PEc) of the third IGF-1 isoform, IGF-1Ec, in prostate cancer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Med
Hauptverfasser: Armakolas, Athanasios, Kaparelou, Maria, Dimakakos, Andreas, Papageorgiou, Efstathia, Armakolas, Nikolaos, Antonopoulos, Athanasios, Petraki, Constantina, Lekarakou, Maria, Lelovas, Pavlos, Stathaki, Martha, Psarros, Constantinos, Donta, Ismene, Galanos, Panos S, Msaouel, Paul, Gorgoulis, Vassilis G, Koutsilieris, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: ScholarOne 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4461578/
https://ncbi.nlm.nih.gov/pubmed/25569803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2014.00222
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