BP180 dysfunction triggers spontaneous skin inflammation in mice

BP180, also known as collagen XVII, is a hemidesmosomal component and plays a key role in maintaining skin dermal/epidermal adhesion. Dysfunction of BP180, either through genetic mutations in junctional epidermolysis bullosa (JEB) or autoantibody insult in bullous pemphigoid (BP), leads to subepider...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Zhang, Yang, Hwang, Bin-Jin, Liu, Zhen, Li, Ning, Lough, Kendall, Williams, Scott E., Chen, Jinbo, Burette, Susan W., Diaz, Luis A., Su, Maureen A., Xiao, Shengxiang, Liu, Zhi
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016813/
https://ncbi.nlm.nih.gov/pubmed/29866844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721805115
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