Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson’s disease

Parkinson’s disease (PD) is characterized as a chronic and progressive neurodegenerative disorder, and the deposition of specific protein aggregates of α-synuclein, termed Lewy bodies, is evident in multiple brain regions of PD patients. Although there are several available medications to treat PD s...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Ren, Qian, Ma, Min, Yang, Jun, Nonaka, Risa, Yamaguchi, Akihiro, Ishikawa, Kei-ichi, Kobayashi, Kenta, Murayama, Shigeo, Hwang, Sung Hee, Saiki, Shinji, Akamatsu, Wado, Hattori, Nobutaka, Hammock, Bruce D., Hashimoto, Kenji
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2018
Schlagworte:
PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016799/
https://ncbi.nlm.nih.gov/pubmed/29735655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802179115
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