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Targeting multiple opioid receptors – improved analgesics with reduced side effects?
Classical opioid analgesics, including morphine, mediate all of their desired and undesired effects by specific activation of the μ‐opioid receptor (μ receptor). The use of morphine for treating chronic pain, however, is limited by the development of constipation, respiratory depression, tolerance a...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6016677/ https://ncbi.nlm.nih.gov/pubmed/28378462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13809 |
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