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Targeting multiple opioid receptors – improved analgesics with reduced side effects?
Classical opioid analgesics, including morphine, mediate all of their desired and undesired effects by specific activation of the μ‐opioid receptor (μ receptor). The use of morphine for treating chronic pain, however, is limited by the development of constipation, respiratory depression, tolerance a...
Uloženo v:
| Vydáno v: | Br J Pharmacol |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6016677/ https://ncbi.nlm.nih.gov/pubmed/28378462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13809 |
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