Antinociceptive effects of novel histamine H(3) and H(4) receptor antagonists and their influence on morphine analgesia of neuropathic pain in the mouse

BACKGROUND AND PURPOSE: The histaminergic system is a promising target for the development of new analgesics, as histamine H(3) and H(4) receptors are expressed in regions concerned with nociceptive transmission. Here we have determined the analgesic effects of new H(3) and H(4) receptor antagonists...

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Bibliografske podrobnosti
izdano v:Br J Pharmacol
Main Authors: Popiolek‐Barczyk, Katarzyna, Łażewska, Dorota, Latacz, Gniewomir, Olejarz, Agnieszka, Makuch, Wioletta, Stark, Holger, Kieć‐Kononowicz, Katarzyna, Mika, Joanna
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Research Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016676/
https://ncbi.nlm.nih.gov/pubmed/29486058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14185
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