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Eleven residues determine the acyl chain specificity of ceramide synthases

Lipids display large structural complexity, with ∼40,000 different lipids identified to date, ∼4000 of which are sphingolipids. A critical factor determining the biological activities of the sphingolipid, ceramide, and of more complex sphingolipids is their N-acyl chain length, which in mammals is d...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Tidhar, Rotem, Zelnik, Iris D., Volpert, Giora, Ben-Dor, Shifra, Kelly, Samuel, Merrill, Alfred H., Futerman, Anthony H.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016465/
https://ncbi.nlm.nih.gov/pubmed/29632068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001936
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