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Eleven residues determine the acyl chain specificity of ceramide synthases
Lipids display large structural complexity, with ∼40,000 different lipids identified to date, ∼4000 of which are sphingolipids. A critical factor determining the biological activities of the sphingolipid, ceramide, and of more complex sphingolipids is their N-acyl chain length, which in mammals is d...
Guardat en:
| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6016465/ https://ncbi.nlm.nih.gov/pubmed/29632068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.001936 |
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