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A rapid ceramide synthase activity using NBD-sphinganine and solid phase extraction

Ceramides are synthesized by six mammalian ceramide synthases (CerSs), each of which uses fatty acyl-CoAs of different chain lengths for N-acylation of the sphingoid long-chain base. We now describe a rapid and reliable CerS assay that uses a fluorescent N-[6-[(7-nitrobenzo-2-oxa-1,3-diazol-4-yl) (N...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Tidhar, Rotem, Sims, Kacee, Rosenfeld-Gur, Eden, Shaw, Walter, Futerman, Anthony H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274067/
https://ncbi.nlm.nih.gov/pubmed/25368106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D052001
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