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CD4(+) T Cell Fate Decisions Are Stochastic, Precede Cell Division, Depend on GITR Co-Stimulation, and Are Associated With Uropodium Development

During an immune response, naïve CD4(+) T cells proliferate and generate a range of effector, memory, and regulatory T cell subsets, but how these processes are co-ordinated remains unclear. A traditional model suggests that memory cells use mitochondrial respiration and are survivors from a pool of...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Cobbold, Stephen P., Adams, Elizabeth, Howie, Duncan, Waldmann, Herman
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015874/
https://ncbi.nlm.nih.gov/pubmed/29967616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01381
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