Epigenetic Regulation of Aldosterone Synthase Gene by Sodium and Angiotensin II

BACKGROUND: DNA methylation is believed to be maintained in adult somatic cells. Recent findings, however, suggest that all methylation patterns are not stable. We demonstrate that stimulatory signals can change the DNA methylation status around transcription factor binding sites and a transcription...

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Vydáno v:J Am Heart Assoc
Hlavní autoři: Takeda, Yoshimichi, Demura, Masashi, Wang, Fen, Karashima, Shigehiro, Yoneda, Takashi, Kometani, Mitsuhiro, Hashimoto, Atsushi, Aono, Daisuke, Horike, Shin‐ichi, Meguro‐Horike, Makiko, Yamagishi, Masakazu, Takeda, Yoshiyu
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015301/
https://ncbi.nlm.nih.gov/pubmed/29739797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.008281
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