Epigenetic Regulation of Aldosterone Synthase Gene by Sodium and Angiotensin II

BACKGROUND: DNA methylation is believed to be maintained in adult somatic cells. Recent findings, however, suggest that all methylation patterns are not stable. We demonstrate that stimulatory signals can change the DNA methylation status around transcription factor binding sites and a transcription...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Takeda, Yoshimichi, Demura, Masashi, Wang, Fen, Karashima, Shigehiro, Yoneda, Takashi, Kometani, Mitsuhiro, Hashimoto, Atsushi, Aono, Daisuke, Horike, Shin‐ichi, Meguro‐Horike, Makiko, Yamagishi, Masakazu, Takeda, Yoshiyu
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015301/
https://ncbi.nlm.nih.gov/pubmed/29739797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.008281
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