Epigenetic Regulation of Aldosterone Synthase Gene by Sodium and Angiotensin II

BACKGROUND: DNA methylation is believed to be maintained in adult somatic cells. Recent findings, however, suggest that all methylation patterns are not stable. We demonstrate that stimulatory signals can change the DNA methylation status around transcription factor binding sites and a transcription...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Takeda, Yoshimichi, Demura, Masashi, Wang, Fen, Karashima, Shigehiro, Yoneda, Takashi, Kometani, Mitsuhiro, Hashimoto, Atsushi, Aono, Daisuke, Horike, Shin‐ichi, Meguro‐Horike, Makiko, Yamagishi, Masakazu, Takeda, Yoshiyu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015301/
https://ncbi.nlm.nih.gov/pubmed/29739797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.008281
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