Pyruvate dehydrogenase complex plays a central role in brown adipocyte energy expenditure and fuel utilization during short-term beta-adrenergic activation

Activation of brown adipose tissue (BAT) contributes to total body energy expenditure through energy dissipation as heat. Activated BAT increases the clearance of lipids and glucose from the circulation, but how BAT accommodates large influx of multiple substrates is not well defined. The purpose of...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Held, Ntsiki M., Kuipers, Eline N., van Weeghel, Michel, van Klinken, Jan Bert, Denis, Simone W., Lombès, Marc, Wanders, Ronald J., Vaz, Frédéric M., Rensen, Patrick C. N., Verhoeven, Arthur J., Boon, Mariëtte R., Houtkooper, Riekelt H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015083/
https://ncbi.nlm.nih.gov/pubmed/29934543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27875-3
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