Precision therapeutic targeting of human cancer cell motility

Increased cancer cell motility constitutes a root cause of end organ destruction and mortality, but its complex regulation represents a barrier to precision targeting. We use the unique characteristics of small molecules to probe and selectively modulate cell motility. By coupling efficient chemical...

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Vydáno v:Nat Commun
Hlavní autoři: Xu, Li, Gordon, Ryan, Farmer, Rebecca, Pattanayak, Abhinandan, Binkowski, Andrew, Huang, Xiaoke, Avram, Michael, Krishna, Sankar, Voll, Eric, Pavese, Janet, Chavez, Juan, Bruce, James, Mazar, Andrew, Nibbs, Antoinette, Anderson, Wayne, Li, Lin, Jovanovic, Borko, Pruell, Sean, Valsecchi, Matias, Francia, Giulio, Betori, Rick, Scheidt, Karl, Bergan, Raymond
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014988/
https://ncbi.nlm.nih.gov/pubmed/29934502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04465-5
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