Genistein treatment duration effects biomarkers of cell motility in human prostate

BACKGROUND: Long term dietary consumption of genistein by Chinese men is associated with decreased PCa metastasis and mortality. Short term treatment of US men with prostate cancer (PCa) with genistein decreases MMP-2 in prostate tissue. MEK4 regulates MMP-2 expression, drives PCa metastasis, and ge...

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Veröffentlicht in:PLoS One
Hauptverfasser: Zhang, Hu, Gordon, Ryan, Li, Wenqi, Yang, Ximing, Pattanayak, Abhinandan, Fowler, Graham, Zhang, Limin, Catalona, William J., Ding, Yongzeng, Xu, Li, Huang, Xiaoke, Jovanovic, Borko, Kelly, David L., Jiang, Haowen, Bergan, Raymond
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6436751/
https://ncbi.nlm.nih.gov/pubmed/30917169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214078
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