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Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) Promotes Human Prostate Cancer Metastasis

Prostate cancer (PCa) is the second leading cause of cancer death in the US. Death from PCa primarily results from metastasis. Mitogen-activated protein kinase kinase 4 (MAP2K4) is overexpressed in invasive PCa lesions in humans, and can be inhibited by small molecule therapeutics that demonstrate f...

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Autori principali: Pavese, Janet M., Ogden, Irene M., Voll, Eric A., Huang, Xiaoke, Xu, Li, Jovanovic, Borko, Bergan, Raymond C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096757/
https://ncbi.nlm.nih.gov/pubmed/25019290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102289
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