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Why do disordered and structured proteins behave differently in phase separation?

Intracellular membraneless organelles and their myriad cellular functions have garnered tremendous recent interest. It is becoming well accepted that they form via liquid-liquid phase separation (LLPS) of protein mixtures (often including RNA), where the organelles correspond to a protein-rich, drop...

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Bibliografiska uppgifter
I publikationen:Trends Biochem Sci
Huvudupphovsmän: Zhou, Huan-Xiang, Nguemaha, Valery, Mazarakos, Konstantinos, Qin, Sanbo
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014895/
https://ncbi.nlm.nih.gov/pubmed/29716768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2018.03.007
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