Osteocyte intrinsic TGFβ signaling regulates bone quality through perilacunar/canalicular remodeling

Poor bone quality contributes to bone fragility in diabetes, aging, and osteogenesis imperfecta. However, the mechanisms controlling bone quality are not well understood, contributing to the current lack of strategies to diagnose or treat bone quality deficits. TGFβ signaling is a crucial mechanism...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Dole, Neha S., Mazur, Courtney M., Acevedo, Claire, Lopez, Justin P., Monteiro, David A., Fowler, Tristan W., Gludovatz, Bernd, Walsh, Flynn, Regan, Jenna N., Messina, Sara, Evans, Daniel S., Lang, Thomas F., Zhang, Bin, Ritchie, Robert O., Mohammad, Khalid S., Alliston, Tamara
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014615/
https://ncbi.nlm.nih.gov/pubmed/29186693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.10.115
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