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Glucocorticoid suppression of osteocyte perilacunar remodeling is associated with subchondral bone degeneration in osteonecrosis

Through a process called perilacunar remodeling, bone-embedded osteocytes dynamically resorb and replace the surrounding perilacunar bone matrix to maintain mineral homeostasis. The vital canalicular networks required for osteocyte nourishment and communication, as well as the exquisitely organized...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Fowler, Tristan W., Acevedo, Claire, Mazur, Courtney M., Hall-Glenn, Faith, Fields, Aaron J., Bale, Hrishikesh A., Ritchie, Robert O., Lotz, Jeffrey C., Vail, Thomas P., Alliston, Tamara
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361115/
https://ncbi.nlm.nih.gov/pubmed/28327602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44618
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