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Glucocorticoid suppression of osteocyte perilacunar remodeling is associated with subchondral bone degeneration in osteonecrosis

Through a process called perilacunar remodeling, bone-embedded osteocytes dynamically resorb and replace the surrounding perilacunar bone matrix to maintain mineral homeostasis. The vital canalicular networks required for osteocyte nourishment and communication, as well as the exquisitely organized...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fowler, Tristan W., Acevedo, Claire, Mazur, Courtney M., Hall-Glenn, Faith, Fields, Aaron J., Bale, Hrishikesh A., Ritchie, Robert O., Lotz, Jeffrey C., Vail, Thomas P., Alliston, Tamara
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361115/
https://ncbi.nlm.nih.gov/pubmed/28327602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44618
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