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Tissue growth constrained by extracellular matrix drives invagination during optic cup morphogenesis

In the early embryo, the eyes form initially as relatively spherical optic vesicles (OVs) that protrude from both sides of the brain tube. Each OV grows until it contacts and adheres to the overlying surface ectoderm (SE) via an extracellular matrix (ECM) that is secreted by the SE and OV. The OV an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biomech Model Mechanobiol
Hauptverfasser: Oltean, Alina, Huang, Jie, Beebe, David C., Taber, Larry A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014613/
https://ncbi.nlm.nih.gov/pubmed/26984743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-016-0771-8
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