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Tissue growth constrained by extracellular matrix drives invagination during optic cup morphogenesis

In the early embryo, the eyes form initially as relatively spherical optic vesicles (OVs) that protrude from both sides of the brain tube. Each OV grows until it contacts and adheres to the overlying surface ectoderm (SE) via an extracellular matrix (ECM) that is secreted by the SE and OV. The OV an...

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Detalhes bibliográficos
Publicado no:Biomech Model Mechanobiol
Main Authors: Oltean, Alina, Huang, Jie, Beebe, David C., Taber, Larry A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014613/
https://ncbi.nlm.nih.gov/pubmed/26984743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-016-0771-8
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