Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer

BACKGROUND: Hypoxia is associated with a poor prognosis in prostate cancer. This work aimed to derive and validate a hypoxia-related mRNA signature for localized prostate cancer. METHOD: Hypoxia genes were identified in vitro via RNA-sequencing and combined with in vivo gene co-expression analysis t...

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Detalles Bibliográficos
Publicado en:EBioMedicine
Autores principales: Yang, Lingjian, Roberts, Darren, Takhar, Mandeep, Erho, Nicholas, Bibby, Becky A.S., Thiruthaneeswaran, Niluja, Bhandari, Vinayak, Cheng, Wei-Chen, Haider, Syed, McCorry, Amy M.B., McArt, Darragh, Jain, Suneil, Alshalalfa, Mohammed, Ross, Ashley, Schaffer, Edward, Den, Robert B., Jeffrey Karnes, R., Klein, Eric, Hoskin, Peter J., Freedland, Stephen J., Lamb, Alastair D., Neal, David E., Buffa, Francesca M., Bristow, Robert G., Boutros, Paul C., Davicioni, Elai, Choudhury, Ananya, West, Catharine M.L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014579/
https://ncbi.nlm.nih.gov/pubmed/29729848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.04.019
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