Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer

BACKGROUND: Hypoxia is associated with a poor prognosis in prostate cancer. This work aimed to derive and validate a hypoxia-related mRNA signature for localized prostate cancer. METHOD: Hypoxia genes were identified in vitro via RNA-sequencing and combined with in vivo gene co-expression analysis t...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Yang, Lingjian, Roberts, Darren, Takhar, Mandeep, Erho, Nicholas, Bibby, Becky A.S., Thiruthaneeswaran, Niluja, Bhandari, Vinayak, Cheng, Wei-Chen, Haider, Syed, McCorry, Amy M.B., McArt, Darragh, Jain, Suneil, Alshalalfa, Mohammed, Ross, Ashley, Schaffer, Edward, Den, Robert B., Jeffrey Karnes, R., Klein, Eric, Hoskin, Peter J., Freedland, Stephen J., Lamb, Alastair D., Neal, David E., Buffa, Francesca M., Bristow, Robert G., Boutros, Paul C., Davicioni, Elai, Choudhury, Ananya, West, Catharine M.L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014579/
https://ncbi.nlm.nih.gov/pubmed/29729848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.04.019
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