Genetic Variants in CPA6 and PRPF31 Are Associated With Variation in Response to Metformin in Individuals With Type 2 Diabetes

Metformin is the first-line treatment for type 2 diabetes (T2D). Although widely prescribed, the glucose-lowering mechanism for metformin is incompletely understood. Here, we used a genome-wide association approach in a diverse group of individuals with T2D from the Action to Control Cardiovascular...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Diabetes
Hlavní autoři: Rotroff, Daniel M., Yee, Sook Wah, Zhou, Kaixin, Marvel, Skylar W., Shah, Hetal S., Jack, John R., Havener, Tammy M., Hedderson, Monique M., Kubo, Michiaki, Herman, Mark A., Gao, He, Mychaleckyi, Josyf C., McLeod, Howard L., Doria, Alessandro, Giacomini, Kathleen M., Pearson, Ewan R., Wagner, Michael J., Buse, John B., Motsinger-Reif, Alison A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2018
Témata:
Genetics/Genomes/Proteomics/Metabolomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014560/
https://ncbi.nlm.nih.gov/pubmed/29650774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db17-1164
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky