The impact of PI3K inhibitors on breast cancer cell and its tumor microenvironment

The phosphoinositide 3-kinase (PI3K) pathway shows frequent aberrant alterations and pathological activation in breast cancer cells. While PI3K inhibitors have not achieved expectant therapeutic efficacy in clinical trials, and several studies provide promising combination strategies to substantiall...

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Bibliografiske detaljer
Udgivet i:PeerJ
Main Authors: Qin, Hanjiao, Liu, Linlin, Sun, Shu, Zhang, Dan, Sheng, Jiyao, Li, Bingjin, Yang, Wei
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2018
Fag:
Biochemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014315/
https://ncbi.nlm.nih.gov/pubmed/29942710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.5092
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