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Rapid biocompatible macrocyclization of peptides with decafluoro-diphenylsulfone
In this manuscript, we describe modification of Cys-residues in peptides and proteins in aqueous solvents via aromatic nucleophilic substitution (S(N)Ar) with perfluoroarenes (fAr). Biocompatibility of this reaction makes it attractive for derivatization of proteins and peptide libraries comprised o...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6013815/ https://ncbi.nlm.nih.gov/pubmed/30155020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03856a |
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