Predominant Asymmetrical Stem Cell Fate Outcome Limits the Rate of Niche Succession in Human Colonic Crypts

Stem cell (SC) dynamics within the human colorectal crypt SC niche remain poorly understood, with previous studies proposing divergent hypotheses on the predominant mode of SC self-renewal and the rate of SC replacement. Here we use age-related mitochondrial oxidative phosphorylation (OXPHOS) defect...

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Detaylı Bibliyografya
Yayımlandı:EBioMedicine
Asıl Yazarlar: Stamp, Craig, Zupanic, Anze, Sachdeva, Ashwin, Stoll, Elizabeth A., Shanley, Daryl P., Mathers, John C., Kirkwood, Thomas B.L., Heer, Rakesh, Simons, Benjamin D., Turnbull, Doug M., Greaves, Laura C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2018
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013780/
https://ncbi.nlm.nih.gov/pubmed/29748033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.04.017
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