Systemic Acrolein Elevations in Mice With Experimental Autoimmune Encephalomyelitis and Patients With Multiple Sclerosis

Demyelination and axonal injury are the key pathological processes in multiple sclerosis (MS), driven by inflammation and oxidative stress. Acrolein, a byproduct and instigator of oxidative stress, has been demonstrated as a neurotoxin in experimental autoimmune encephalomyelitis (EAE), an animal mo...

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Vydáno v:Front Neurol
Hlavní autoři: Tully, Melissa, Tang, Jonathan, Zheng, Lingxing, Acosta, Glen, Tian, Ran, Hayward, Lee, Race, Nicholas, Mattson, David, Shi, Riyi
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Neurology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013577/
https://ncbi.nlm.nih.gov/pubmed/29963001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00420
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