Systemic Acrolein Elevations in Mice With Experimental Autoimmune Encephalomyelitis and Patients With Multiple Sclerosis

Demyelination and axonal injury are the key pathological processes in multiple sclerosis (MS), driven by inflammation and oxidative stress. Acrolein, a byproduct and instigator of oxidative stress, has been demonstrated as a neurotoxin in experimental autoimmune encephalomyelitis (EAE), an animal mo...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Tully, Melissa, Tang, Jonathan, Zheng, Lingxing, Acosta, Glen, Tian, Ran, Hayward, Lee, Race, Nicholas, Mattson, David, Shi, Riyi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013577/
https://ncbi.nlm.nih.gov/pubmed/29963001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00420
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