Mycobacterium tuberculosis-specific CD4(+) and CD8(+) T cells differ in their capacity to recognize infected macrophages

Containment of Mycobacterium tuberculosis (Mtb) infection requires T cell recognition of infected macrophages. Mtb has evolved to tolerate, evade, and subvert host immunity. Despite a vigorous and sustained CD8(+) T cell response during Mtb infection, CD8(+) T cells make limited contribution to prot...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Yang, Jason D., Mott, Daniel, Sutiwisesak, Rujapak, Lu, Yu-Jung, Raso, Fiona, Stowell, Britni, Babunovic, Greg Hunter, Lee, Jinhee, Carpenter, Steve M., Way, Sing Sing, Fortune, Sarah M., Behar, Samuel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013218/
https://ncbi.nlm.nih.gov/pubmed/29782535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007060
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